Uncoupling of ATP-mediated calcium signaling and dysregulated interleukin-6 secretion in dendritic cells by nanomolar thimerosal

Citation

Evidence Type: Research (Generic)
Goth SR, Chu RA, Gregg JP, Cherednichenko G, Pessah IN. Uncoupling of ATP-mediated calcium signaling and dysregulated interleukin-6 secretion in dendritic cells by nanomolar thimerosal. Environ Health Perspect. 2006 Jul;114(7):1083-91 - Uncoupling of ATP-mediated calcium signaling and dysregulated interleukin-6 secretion in dendritic cells by nanomolar thimerosal. - PubMed - NCBI Score: 0.0/0.0

Discussion

This research exposed a mouse cell line to trace amounts of thimerosal and noticed a change occurring in the cells The research paper itself states that this certainly does not automatically mean that vaccines cause autism It is worth noting that:

  • Since cell lines are a collection of a single type of cell in a petri dish (rather than an entire living animal with all the built in regulatory functions) they are notoriously difficult to work with, producing unusual results for any number of reasons
  • The cell line in question came from mice, not from humans So we cannot draw an immediate conclusion for human applications
  • The changes noticed are not automatically indicative of autism
  • There is an overwhelming amount of evidence showing that thimerosal is not linked to autism

You can read about this research in more detail here:

Strengths/Weaknesses

Conclusions

No strengths or weaknesses have yet been added to this evidence

Conclusion 1

It has been claimed this research is evidence that vaccines (at least those containing thimerosal) cause autism It does not The authors have stated it does not The evidence does not support this claim


Conclusion 2

It is clear that anyone who thinks this research is evidence that vaccines cause autism is more interested in finding any scrap of evidence to support their existing conclusions than they are in what the evidence actually says.


Conclusion 3

This research does not demonstrate that vaccines cause autism. Anyone who says otherwise is spreading misinformation.


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