Measles, mumps, and rubella vaccination and bowel problems or developmental regression in children with autism: population study

Citation

Evidence Type: Research (Data Analysis)
Taylor B, Miller E, Lingam R, Andrews N, Simmons A, Stowe J. Measles, mumps, and rubella vaccination and bowel problems or developmental regression in children with autism: population study. BMJ. 2002;324(7334):393–6 - Measles, mumps, and rubella vaccination and bowel problems or developmental regression in children with autism: population study. - PubMed - NCBI Score: 0.0/0.0

Discussion

The research looked at 473 cases of autism across five health districts in north east London, concentrating on onset of symptoms, age of vaccination, and bowel problems experienced. The research found:

  • The number of children with developmental regression and bowel problems did not change from 1979 to 1998 (with vaccine released in October 1988
  • No difference in rates of bowel problems or regression in those who received the MMR vaccine before onset of symptoms, those who received the MMR vaccine after onset of symptoms, and those who did not get the MMR vaccine
  • A possible link between bowel problems and regression was indicated, but this was unrelated to the MMR vaccine

 

Strengths/Weaknesses

Conclusions

Strength/Weakness 1

The funding came from the Department of Health, who are concerned with health outcomes rather than simply selling more vaccines.


Strength/Weakness 2

Strong strength: Industry Independence

There do not appear to be any conflicts of interest with any of the authors.


Conclusion 1

The research found no link between the MMR vaccine and rate of occurrence of bowel disorders


Conclusion 2

The study found no link between the MMR vaccine and developmental regression


Conclusion 3

The research demonstrates there is no link between the MMR vaccine and onset of autism symptoms.


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